Medicinal chemistry; drug design and development in the areas of anti-vessication agents, vasopressin antagonists, dermatologicals, and cholinesterase inhibitors.

Teaching Interests:

As you might expect, I teach courses in the area of my research expertise. These include a graduate course in synthesis, one in heterocyclic compounds, another in medicinal and pharmaceutical chemistry, and a "gateway" course on organic reaction mechanisms.

Recent Publications and Patents:

C. Guillon, G. Koppel, N. Heindel /et al/. “Azetidinones as vasopressin V1a antagonists,” Bioorg. & Med. Chem., *15* (2007) 2054-2080.

C. F. Ferris, S-f Lu, T. Messenger, C. D. Guillon, N. Heindel, M. Miller, G. Koeppel, F. R. Bruns, and N. G. Simon, “Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior,” Pharmacology, Biochemistry and Behavior, *83* (2006) 169-174.

J. D. Laskin, C. Martey, N. D. Heindel, M. Whittemore, and D. Heck, * “*Fluorescent Tags for Amino Acid and Nucleic Acid Analysis*,”* U.S. Patent 7,150,967 (2006)

J. D. Laskin, D. Heck, N. D. Heindel, A. M. Vetrano, C. Guillon, P. DeMatteo, “Fluorescent Fused-Ring Triazoles that Inhibit Cell Proliferation,” U.S. Patent 7,105,511 (2006)

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R. F. Bruns, C. Guillon, N. D. Heindel, G. A. Koppel, M. Miller, Beta-Lactamyl Vasopressin Antagonists,” U.S.Patent 7,119,083 (2006).

N. D. Heindel, Tina Masciangioli, and Eva von Schaper, eds., “Are Chemistry Journals too Expensive and Inaccessible?,” National Academies Press, ISBN 0-309-09590-5, Washington, DC, 2005.